Antiemetics and cytotoxic drugs.

Use of Cytotoxic Drugs

استفاده روز افزون از داروهای سایتوتوکسیک باعث شده است که پرستاران بیشتر در معرض خطرات این مواد باشند. از این رو خانم جونیت گیبز ضمن مطالعه و بررسی در این زمینه راه هایی را جهت به حداقل رساندن این خطرات مطرح می کند.  

Alopecia and cytotoxic drugs.

policy still right in principle then ? Or is there a risk that the patient may fall between two stools, for lack of what Job describes as a " daysman " ? Experience indicates that this dilemma can and does result in major and minor tragedies: like that of the schoolmaster with " consolidation of the left lower lobe " who presented in the chest ward three months later with an inoperable bronchia...

Cytotoxic Drugs and Wound Repair

Cardiotoxicity of cytotoxic drugs.

Cardiotoxicity is a well-known side effect of several cytotoxic drugs, especially of the anthracyclines and can lead to long term morbidity. The mechanism of anthracycline induced cardiotoxicity seems to involve the formation of free radicals leading to oxidative stress. This may cause apoptosis of cardiac cells or immunologic reactions. However, alternative mechanisms may play a role in anthra...

Antiemetics: a Review

The act of emesis is controlled by the vomiting centre in the medulla, which integrates afferent input from the vestibular system, the chemoreceptor trigger zone (CTZ), the cortex and the gut. Nausea and vomiting induced by several cancer chemotherapy agents is often the most distressing side effect of treatment. The mechanism of action of antiemetic is related to blockage of various type of re...